Page 112 - Malaysian Journal of Health Promotion, Vol 4 (Supplementary 1) 2022

Malaysian Journal of Health Promotion, Vol 4 (Supplementary 1) 2022
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14 MOH-AMM Scientific Meeting 2022 in conjunction with 23 NIH Scientific Conference Abstract Book
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due to ischaemic heart disease (12.85%), lower respiratory infection (9.21%) and breast
cancer (8.73%). According to the age, YLL generally increases as the age increases.
DISCUSSION/CONCLUSION: The leading cause of premature mortality among working age
population was ischaemic heart disease, which are preventable with healthy living habits and
early intervention. Road traffic injuries are also preventable with safe driving habits and safer
road infrastructures. Refining intervention strategies for diseases with preventable risk
factors will not only reduce premature mortality among working age population but also
reduce productivity loss.

ID 128 PREVALENCE OF ANTIBIOTIC RESISTANT ENTEROCOCCI ISOLATED FROM HOSPITALS’
EFFLUENT IN KLANG VALLEY

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1
1
1
Sophia Karen Bakon , Zuraifah Asrah Mohamad , Nur Fatihah Sholehah Zakaria , Mohamad Hairulhisam Hairi ,
1
1
1
2
Ahmad Fadhli Abdul Hamid , Nurul-Ain Sukati , Naziatul Maisyarah Amir , Hazimah Hashim , Mohamed Yazid
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3
Kuman , Norazag Ahmad , Rafiza Shaharudin
1 Environmental Health Research Centre, Institute for Medical Research, Ministry of Health Malaysia, National
Institutes of Health, Shah Alam, Selangor, Malaysia
2 Selangor State Health Department, Shah Alam, Selangor
3 Engineering Service Division, Ministry of Health Malaysia, Putrajaya, Malaysia
4 Infectious Disease Research Centre, Institute for Medical Research, Ministry of Health Malaysia, National
Institutes of Health, Shah Alam, Selangor, Malaysia

INTRODUCTION: The extensive use of antibiotics in healthcare systems attribute to the
increased abundance of antibiotic resistance bacteria in the environment which become a
global public health concern. Enterococcus faecium and Enterococcus faecalis are two
enterococcal species that are pathogenic to human, commonly isolated from hospital
acquired infections. Therefore, we aim to determine the prevalence of antibiotic resistant
enterococci from effluent of 2 hospitals in Klang Valley against vancomycin and ciprofloxacin.
METHODS: We sampled the hospitals’ effluent and cultured on Chromogenic Enterococcus
agar to isolate the bacteria of interest. Antibiotic sensitivity test was performed on isolates
according to the Kirby Bauer disk diffusion method following the CLSI standard.
RESULTS: From 10 isolates of E. faecium from Hospital A, 80% were resistant towards
vancomycin and 20% were susceptible while only 10% were resistant, 60% had intermediate
resistance and 30% were susceptible towards ciprofloxacin. Meanwhile, all isolate (n=10) of
E faecium from Hospital B were resistant towards vancomycin but susceptible towards
ciprofloxacin. On the other hand, 90%(n=10) of E. faecalis isolated from Hospital A were
resistant and 10% were susceptible towards vancomycin while 90% had intermediate
resistance and 10% were susceptible towards ciprofloxacin. As for E. faecalis isolated from
Hospital B, 90%(n=10) were resistant and 10% were susceptible towards vancomycin and 70%
were susceptible and 30% were intermediate towards ciprofloxacin.
DISCUSSION/CONCLUSION: This finding suggests that the use of antibiotics in hospitals has
led to the spread and emergence of resistant bacteria in the environment. Therefore, the
surveillance of its spread in the environment is needed while implementing strategies to limit
the use of antibiotics and upgrading the sewage treatment facilities in the hospitals should
be considered.

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