Page 62 - Malaysian Journal of Health Promotion, Vol 4 (Supplementary 1) 2022

Malaysian Journal of Health Promotion, Vol 4 (Supplementary 1) 2022
14 MOH-AMM Scientific Meeting 2022 in conjunction with 23 NIH Scientific Conference Abstract Book
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order to identify and prioritise main health issues for appropriate and efficient Public Health
Intervention.
METHODS: A descriptive retrospective cross-sectional study was conducted. Medical records
from January 2017 till December 2021 of selected subjects were reviewed and study data
were extracted. Diagnosis profile was categorized based on ICD-10 as in Buku Polisi Operasi
Klinik Bergerak 1 Malaysia. Data was analysed using the Statistical Package for Social Sciences
version 26. Descriptive statistics was computed.
RESULTS: A total of 208 medical records were reviewed. Majority were female (55.8%) and
Indians (37.0%). The mean (SD) age of attendees was 24.20 years. 67.8% of the attendees to
MHC were walk-in patients. The four main diagnosis profile were acute upper respiratory
infection (40.9%), encounter health services for investigation and examination (19.2%),
health services related to reproduction (5.8%) and hypertension (5.8%).
DISCUSSION/CONCLUSION: In conclusion, Public Health Intervention Programme for MHC
services in Hulu Selangor District should focus on promoting nutritious food intake and good
hygiene practice. Safe motherhood and reproductive health programme also should be
considered together with the health screening activities for early detection of chronic
diseases.

ID 38 NON-ALCOHOLIC FATTY LIVER DISEASE, THE ASSOCIATION WITH CANCERS AND
PREVALENCE: A SYSTEMATIC REVIEW AND META-ANALYSIS.

1
2
2
1
Nur Hasnah Maamor , Nor Asiah Muhamad , Zuraifah Asrah Mohamad , Sophia Karen Bakon , Mohd Hatta
2
3
1
1
4
Abdul Mutalip , Fatin Norhasny Leman , ‘Izzah ‘Athirah Rosli , Tahir Aris , Nai Ming Lai , Muhammad Radzi Abu
Hassan 5
1 Sector For Evidence-Based Healthcare, National Institutes Of Health, Ministry Of Health, Setia Alam, Selangor,
Malaysia
2 Institute For Medical Research, National Institutes Of Health, Ministry Of Health, Setia Alam, Selangor, Malaysia
3 Institute For Public Health, National Institutes Of Health, Ministry Of Health, Setia Alam, Selangor, Malaysia
5
4 School Of Medicine, Taylor’s University, Subang Jaya, Selangor, Malaysia. Department Of Medicine, Hospital
Sultanah Bahiyah, Ministry Of Health, Alor Setar, Kedah, Malaysia

Background: Non-alcoholic fatty liver disease (NAFLD) is a common liver disorder that also
plays a role in cancer development around the world.
Method: We systematically searched PubMed, ProQuest, Scopus, and Web of Science from
database inception to Mac 2022, to identify eligible observational studies reporting the
prevalence of NAFLD and examining the risk of incident cancers amongst adult (age ≥18 years)
individuals. Data from selected studies were extracted, and meta-analysis was performed
using random-effects models to obtain pool prevalence with 95% CIs. The quality of the
evidence was assessed through Newcastle Ottawa Scale (NOS).
Results: We identified 11 studies that met our inclusion criteria, involving 222,523 adults and
3 types of cancer; hepatocellular carcinoma (HCC), breast and other types of extrahepatic
cancer. Overall prevalence of NAFLD and cancer was 26.0% (95% CI: 16.0 – 35.0), while 25.0%
of people had NAFLD and HCC (95% CI: 7.0 – 42.0). NAFLD and breast cancer had the highest
prevalence out of the three forms of cancer, at 30.0% (95% CI: 14.0 – 45.0). While the pool
prevalence for NAFLD and other cancer was 21.0% (95% CI: 12.0 – 31.0).
Conclusion: The finding suggested that NAFLD is significantly increased the risk of cancer not
only in the liver but also in other organs such as the breast and bile. Since the global
prevalence of NAFLD is increasing, policymakers must seek to reverse the trend by increasing
NAFLD awareness and promoting as well as encouraging healthy lifestyle environments.

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