Page 66 - Malaysian Journal of Health Promotion, Vol 4 (Supplementary 1) 2022

Malaysian Journal of Health Promotion, Vol 4 (Supplementary 1) 2022
14 MOH-AMM Scientific Meeting 2022 in conjunction with 23 NIH Scientific Conference Abstract Book
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demonstrated an increase in invasive properties of the treated cells as compared to the
untreated ones, in vitro.
DISCUSSION/CONCLUSION: These results emphasized the role of CRH signalling in the
metastatic potential of breast cancer cells. Its action may involve cross-talks with other
molecular networks that eventually trigger the transcription of EMT-related genes and hence
enable the cells to acquire invasive phenotype.

ID 44 ESTIMATING THE COVID-19 MORTALITY BURDEN IN MALAYSIA IN 2021

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LeeAnn Tan , Shubash Shander Ganapathy , Yee Mang Chan , Nazirah Alias , Nur Hamizah Nasaruddin , Wan-
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Fei Khaw , Azahadi Omar
1 Institute for Public Health, National Institutes of Health, Ministry of Health Malaysia
2 Sector for Biostatistics and Data Repository, National Institutes of Health, Ministry of Health Malaysia

INTRODUCTION: Measuring years of life lost (YLL) owing to premature death from a disease
offers a more appropriate metric than absolute death counts for measuring the mortality
burden of a disease on a population. This study estimates the burden of mortality attributable
to COVID-19 by measuring YLL to COVID-19 in Malaysia in 2021.
METHODS: Data on individual COVID-19 deaths in Malaysia that occurred in 2021 were
obtained from the Ministry of Health’s GitHub repository. We calculated YLL attributable to
COVID-19 using life expectancy data from the national life table for 2017 published by the
Department of Statistics Malaysia (DOSM), and compared the burden of COVID-19 relative to
deaths from other leading causes of disease and injury in the country as reported by the
Malaysian Burden of Disease and Injury Study 2017.
RESULTS: Males lost 367,995 YLL and females lost 297,033 YLL (corresponding to 20.7 and
22.4 years lost per person who died of COVID-19, respectively) in 2021 in Malaysia. The state
of Selangor saw the highest YLL rate of 3427.1 years per 100,000 people. The total mortality
burden attributable to COVID-19 is higher than that caused by ischaemic heart disease, which
was the leading cause of fatal burden in the country in pre-pandemic times.
DISCUSSION/CONCLUSION: These YLL estimates highlight that the COVID-19 pandemic has
caused a considerable mortality impact on the Malaysian population, and lend perspective to
the debate on whether the implementation of radical mitigation measures including multiple
movement control orders (i.e., lockdowns) were necessary.

ID 45 INVOLVEMENT IN COVID-19 CARE INTENSIFIES THE STRESSORS AMONG HEALTHCARE
WORKERS DURING PANDEMIC

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Muhamad Khairul Nazrin Khalil , Mohd Shaiful Azlan , Norhafizah Sahril , Mohd Aznuddin Abd Razak , Nik Adilah
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Shahein , Muhammad Solihin Rezali , Fatin Athirah Tahir , Muhammad Azri Adam Adnan , Nor’ain Ab Wahab ,
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Norliza Shamsuddin , Liew Siaw Hun
1 Family Health Research Centre, Institute of Public Health, National Institutes of Health

INTRODUCTION: The COVID-19 pandemic has a huge impact on the mental health of
healthcare workers (HCWs). Since the majority but not all HCWs were directly involved with
COVID-19 care, this study was conducted to investigate the association between direct
involvement in COVID-19 care and stressors among HCWs.
METHODS: This study was part of Mental Health Status among Healthcare Workers in
Malaysia During the COVID-19 Pandemic (MentalStatCOVID_HCW), a cross-sectional study
conducted using computer-assisted self-interview from July to September 2021. The stressors
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