Page 60 - Malaysian Journal of Health Promotion, Vol 4 (Supplementary 1) 2022

Malaysian Journal of Health Promotion, Vol 4 (Supplementary 1) 2022
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14 MOH-AMM Scientific Meeting 2022 in conjunction with 23 NIH Scientific Conference Abstract Book
ID 34 ASSOCIATION OF PARENTAL REFUSAL FACTORS FOR VACCINATIONS IN CHILDREN: A
SYSTEMATIC REVIEW AND META-ANALYSIS

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Nor Asiah Muhamad , Nur Hasnah Maamor , Nor Soleha Mohd Dali , Fatin Norhasny Leman , ‘Izzah ‘Athirah
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Rosli , Zuraifah Asrah Mohamad , Sophia Karen Bakon , Mohd Hatta Abdul Mutalip , Fatin Athira Tahir , Tahir
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Aris , Muhammad Radzi Abu Hassan
1 Sector for Evidence-based Healthcare, National Institute of Health, Ministry of Health
2 Institute for Medical Research, National Institutes of Health, Ministry of Health
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Institute for Public Health, National Institutes of Health, Ministry of Health
4 Clinical Research Centre, Sultanah Bahiyah Hospital, Alor Star, Kedah, Malaysia

INTRODUCTION: Parental concerns about vaccines have led to a wide spectrum of decisions
varying from parents completely refusing all vaccinations to only delaying vaccinations so that
they are more spread out. This review aimed to systematically compare and pool the
prevalence and the factors influencing vaccine refusal or hesitancy among parents across the
globe.
METHODS: We searched electronic databases from inception to Mac 2022. We included
population-based studies that reported prevalence of parental refusal or hesitancy. We used
random effects meta-analyses to pool prevalence estimates of parental refusal and hesitancy.
RESULTS: A total of 244 studies met our inclusion criteria comprising data on 1,857,905 adults
from 6 regions across the globe. From these 244 studies, we identified various reasons for
parental' refusal which include religious beliefs, concerns about vaccine safety and efficacy,
lack of awareness, and poor knowledge of vaccine-preventable diseases. Africa has the
highest pooled prevalence of vaccine refusal was 32.0% (95% CI: 0.06 – 0.58) with a high-level
of heterogeneity between studies (I2 = 99.5%, P = 0.001). Meanwhile in South America, the
overall pooled prevalence of vaccine refusal is the lowest; 18.0% (95% CI: 0.03 – 0.32) with a
high-level of heterogeneity between studies (I2 = 99.3%, P = 0.001).
CONCLUSION: Many studies have revealed that vaccine hesitancy among parents are due to
various possible factors, such as religious reasons, personal beliefs or philosophical reasons,
safety concerns, and a desire for more information from healthcare providers as well as
factors related to availability, accessibility, affordability, and acceptability of vaccinations.

ID 35 APPRAISING THE UPTAKE OF HRP AREAS UNDER 12TH MALAYSIA PLAN: A REVIEW OF
THE EVIDENCE FOR 2021

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Nor Asiah Muhamad , Fatin Norhasny Leman , Nur Hasnah Ma’amor , S Asmaliza Ismail
1 Sector for Evidence based Healthcare, National Institutes of Health, Ministry of Health
2 Office of the Manager, National Institutes of Health, Ministry of Health

INTRODUCTION: Research is essential for evidence-based decision making. Evaluation and
monitoring of the uptake for health research priorities (HRP) is complex and variably
regulated. In this review, we look at the uptake of HRP key areas for 2021.
METHODS: We conducted a search to identify all studies that were registered under NMRR
for 2021. We then characterized these research topics under eight key areas from HRP,
domain, and ranking.
RESULTS: We identified 2946 research that were registered under NMRR of which 1521
approved by MREC. Of these, 1256 were under HRP areas. From 1256, health system area
had the highest uptake, 450 research, followed by 345 research under communicable disease
and 255 research under non-communicable disease. Meanwhile mental health, oral health,

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