Page 21 - IMR ANNUAL REPORT 2021: INSTITUTE FOR MEDICAL RESEARCH
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8     IMR ANNUAL REPORT 2021


                    Paraneoplastic Neurological Syndrome (PNS) anti-
               9                                                                     518           660
                    bodies
                    Skin Antibodies: Anti-BP 180, Anti-BP 230: Anti-Des-
                                                                                     78
               10   moglein-1 & Anti-Desmoglein-3                                    334           203
       ALLERGY AND IMMUNOLOGY  RESEARCH CENTRE (AIRC)  12  *Anti-Cardiolipin Antibodies (IgM & IgG)  2756  1233
                                                                                                   696
                    Specific Liver Antibodies Panel (SLA)
               11
                                                                                    1378
                    *Anti-Cyclic Citrullinated Antibody (CCP)
               13
                                                                                                   1925
                    *Tissue antibody

                    b) Anti-Mitochondrial Antibodies (AMA)
               14   a) Anti-Smooth Muscle Antibodies (ASMA)                         3542           2540
                    c) Anti-Liver Kidney Microsomal Antibodies (LKM)
                    d) Anti-Gastric Parietal Cell Antibodies (APC)


               15   *Extractable nuclear antigen (ENA)                              3522           2777
               16   *Anti –β2-Glycoprotein antibodies (IgG & IgM)                   1239           1307

                    *Anti-Neutrophil Cytoplasmic Antibodies (ANCA)
                    a)     C-ANCA
               17                                                                   2244           1664
                    b)     P-ANCA


                    * Anti-Neutrophil Cytoplasmic Antibodies (ANCA)
                    a)     Anti - myeloperoxidase (MPO)
               18                                                                   2244           1664
                    b)     Anti-Proteinase 3 (PR3)

                    TOTAL                                                          21912          18739

            (*) Tests were handed over to MOH hospitals in October 2021

            Primary Immunodeficiency Unit


            The Primary Immunodeficiency (PID) unit offers two immunologic screening tests;
            namely the Lymphocyte Subset (TBNK) Enumeration Test and Immunoglobulin
            and Complement Quantitation. The unit also offers specific functional assays;
            Dihydrorhodamine (DHR) test for the chronic granulomatous disease, Bruton’s
            tyrosine kinase (BTK) by flow cytometry for X-linked agammaglobulinemia and
            lymphocyte proliferation assay for assessment of immune function in selective
            cases suspected with T cells defects. The workload for 2021 is shown in the
            following table.


                                                                  ) Unit W
                                                                            or
                                                          c
                                                           y (P
                                                                ID
                                                                                  a
                                                                                    d in 2
                                                                                          0
                                                                               klo
                                                                                            21
                             r
                           P
                           Primary Immunodeficiency (PID) Unit Workload in 2021
                                              odeficien
                                   y Immun
                             imar
               No.                         Name of tests                             Tests performed
                 1     Lymphocyte Subset (TBNK) Enumeration Test                            1637
                 2     Immunoglobulin A                                                     2080
                 3     Immunoglobulin G                                                     2219
                 4     Immunoglobulin M                                                     2007
                 5     Complement C3                                                        2092
                 6     Complement C4                                                        2092
                 7     Dihydrorhodamine (DHR) test                                           158
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