Page 81 - Living-on-the-frontline-of-COVID-19-in-MCO-and-CMCO

Treatment of Kawasaki Disease (Acute Phase)

The treatment of Kawasaki Disease during acute phase is IV immunoglobulin

(IVIG) 2g/kg as a single infusion over 12 hours. Preferably, IVIG should be given
within the first 10 days of fever. With this, coronary aneurysm has been reduced to

5% or less. Without treatment, the incidence of coronary artery aneurysm can be as
high as 25%.

Concomitantly, we also give an anti-inflammatory dose of aspirin. In most of the
Asian countries and in Europe, we give 30 to 50mg/kg/day orally in 3 or 4 divided
doses. In some other countries like in the United States, they still give 80 to 100mg/

kg/day 6 to 8 hourly. This child will continue the aspirin treatment until the 14th
day of illness, or until the patient is afebrile for 48 hours.