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Introduction to Multisystem Inflammatory
Syndrome in Children (MIS-C)
We do not see any cases of Multisystem Inflammatory Syndrome in Children (MIS-
C) in this country. MIS-C was first alerted to the world by the NHS in the United
Kingdom on the 24th April 2020. Then the Royal College Paediatrics and Child
Health (RCPCH) came out with a guidance on paediatric multisystem
inflammatory syndrome temporally associated with COVID-19. The UK group
actually published a letter to alert the world that there is a similar Kawasaki
Disease-like Illness in COVID-19 patients. I shall share this briefly with you later.
There is also an Italian group that published this paper in Lancet [1]. They shared
10 patients with classic and incomplete Kawasaki Disease. There is another
circulation paper from France and Switzerland that shared data on patients who
have acute heart failure in MIS-C as well [2].