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Introduction to Multisystem Inflammatory


                                    Syndrome in Children (MIS-C)










               We do not see any cases of Multisystem Inflammatory Syndrome in Children (MIS-

               C) in this country. MIS-C was first alerted to the world by the NHS in the United
               Kingdom on the 24th April 2020. Then the Royal College Paediatrics and Child

               Health   (RCPCH)   came   out   with   a   guidance   on   paediatric   multisystem
               inflammatory   syndrome   temporally   associated   with   COVID-19.   The   UK   group
               actually  published  a letter  to  alert  the  world   that there is a  similar  Kawasaki

               Disease-like Illness in COVID-19 patients. I shall share this briefly with you later.

               There is also an Italian group that published this paper in Lancet [1]. They shared

               10   patients   with   classic   and   incomplete   Kawasaki   Disease.   There   is   another
               circulation paper from France and Switzerland that shared data on patients who
               have acute heart failure in MIS-C as well [2].
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