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WHO Case Definition
With all these alerts, WHO finally came out with a standardized definition. This
definition is actually evolving. This is what I downloaded from the internet 2 days
ago. WHO may just update it every 2 weeks or so.
Diagram 13: WHO case definition of MIS-C
The criteria are that children and adolescents 0 to 19 years old of age with fever 3 or
more days, AND 2 of the following:
(1) Conjunctivitis and (2)ECHO findings of coronary artery abnormalities are the
same as Kawasaki Disease; (3)hypotensive or shock, (4)evidence of coagulopathy
which is not seen in Kawasaki Disease, and also (5)acute gastroenteritis problems
which is seen more common in MIS-C as compared to Kawasaki Disease.
AND
raised inflammatory markers such as ESR, C-reactive protein (CRP) or
procalcitonin, AND
no other obvious causes of inflammation which includes bacterial infection,
staphylococcal or streptococcal shock syndrome.
AND
