Page 26 - Care-for-vulnerable-populations-during-COVID-19-pandemic

The significance of elevated ALT, AST, bilirubin, ALP

What is significant of elevated liver biochemistry?

Based on a study in China with more than 400 patients, abnormal liver function tests itself is
associated with higher risk of severe COVID-19. In another study from New York which
involved more than 1,000 patients, the multivariable analysis showed that liver injury at
presentation was having an odd ratio of 2.5. And it is independently associated with higher risk
of poor composite outcome ICU admission and/or death. Other factors include age, number of
comorbidities, respiratory problems like tachypnea and severe hypoxia.