Page 69 - Malaysian Journal of Health Promotion, Vol 4 (Supplementary 1) 2022

Malaysian Journal of Health Promotion, Vol 4 (Supplementary 1) 2022
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14 MOH-AMM Scientific Meeting 2022 in conjunction with 23 NIH Scientific Conference Abstract Book
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healthcare delivery (2015), and covering more extensive healthcare services and informal
caregiving (2019). Refinements were also made at the level of questions to refine its clarity.
The question “Has a doctor/nurse ever told you that you have diabetes or needed
investigation or treatment for diabetes?” (1986) was improvised to “Has a medical personnel
ever told you that you have diabetes?” (2011), and further refined to “Have you ever been
told by a doctor or Assistant Medical Officer that you have diabetes?” (2019).
DISCUSSION/CONCLUSION: The health system is a dynamic entity and continuously evolving.
The review of healthcare demand scopes and questions shows that assessments should be
cognizant of changes in the health system and policy priorities.

ID 49 SPIKE PROTEIN ANTIBODY DEVELOPMENT IN ADULTS WITH COMORBIDITIES POST
COVID-19 VACCINATION

Mohd Hatta bin Abdul Mutalip, Nurdiyana Farhana binti Mat Tamizi, Hamizatul Akmal binti Ab Hamid, Eida
Nurhadzira Muhammad, Chong Zhuo Lin.
Institute for Public Health, National Institutes of Health Malaysia

INTRODUCTION: Antibodies produced in response to COVID-19 immunization are essential
for protection against severe COVID-19 infection. Data on the development of spike protein
antibodies (S-ab) in adults with comorbidities is scarce. Hence, this study observed the
development of S-ab in adults with comorbidities following post-vaccination.
METHODS: Data were obtained from the IMSURE study, a prospective cohort study design
which was conducted among adults aged ≥18 years who mandatorily received two vaccine
shots. Blood was drawn and tested for S-ab at the baseline and subsequent follow-ups.
Participants reported comorbidities if they had been diagnosed with any of the specified
conditions by a medical practitioner. For each follow-up, an independent t-test was used to
examine the mean difference in S-ab titre with comorbidity status.
RESULTS: A total of 1,837 respondents aged ≥18 years were recruited and 37.8% reported
having comorbidities which was more common among older adults. At baseline, there were
no mean differences in S-ab titre by comorbidity status. Without controlling for the types of
vaccine received, S-ab titre was found lower among comorbid adults as compared to non-
comorbid adults after the first dose (p-value<0.001), completed vaccination (p-value=0.020),
and 3 months post vaccination (p-value<0.001). A higher mean of S-ab titre was observed
among comorbid adults at 6 months post-vaccination (p-value<0.001).
DISCUSSION/CONCLUSION: S-ab titres were significantly lower in adults with comorbidities
compared to non-comorbid adults. Significant increases in S-ab titres after 6 months could be
attributed to the mandatory booster policy for older adults and Sinovac recipients.

ID 50 ANXIETY AND ITS ASSOCIATED FACTORS AMONG HEALTHCARE WORKERS (HCWs) IN
MALAYSIA DURING COVID-19 PANDEMIC

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Muhammad Azri Adam Adnan , Norhafizah Sahril , Chan Ying Ying , Mohamad Aznuddin Abd Razak , Nik Adilah
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Shahein , Muhammad Solihin Rezali , Fatin Athirah Tahir , Muhamad Khairul Nazrin Khalil , Nor’ain Ab Wahab ,
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Norliza Shamsuddin , Liew Siaw Hun , Noor Ani Ahmad , Mohd Shaiful Azlan Kassim
1 Institute for Public Health, National Institute of Health, Ministry of Health, Malaysia

INTRODUCTION: The COVID-19 pandemic has burdened healthcare workers (HCWs)
physically and mentally. This study aims to assess the prevalence of anxiety and its associated
factors among HCWs working in the Ministry of Health, Malaysia during COVID-19 pandemic.
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