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Table 1.2: MIC50, MIC90 and MIC values MIC range, (µg/mL) for C. albicans in
2018-2020.

Antifungals MIC50 MIC90 Range

Amphotericin B 0.38 0.5 0.012 - 32

Fluconazole 0.25 1 0.006 - 256

Itraconazole 0.064 0.19 0.003 - 32

Posaconazole * * 0.015 - 0.03

Voriconazole 0.008 2 0.002 - 32

Anidulafungin 0.006 0.023 0.001 - 32

Caspofungin 0.38 0.5 0.004 - 8

Micafungin 0.06 0.12 0.004 - 8

5-Fluorocytosine 0.05 1 0.03 - 64

*The number of isolates tested were too low.

The antifungal susceptibility patterns and percentages are shown in Table
1.3. and Figure 1.1.

Table 1.3: Antifungal susceptibility patterns and percentages of C. albicans.

Antifungal Percentage (n) of isolates
agents
S I SDD R WT NWT

Anidulafungin 96.0% (222) 0.0% (0) 4.0% (1)

Caspofungin 66.2% (149) 32.9% (74) 0.9% (2)

Micafungin 94.2% (49) 3.8% (2) 1.9% (1)

Voriconazole 88.1% (200) 0.4% (1) 11.5% (26)

Fluconazole 92.9% (210) 1.8% (4) 5.3% (12)

Posaconazole 100.0% (3) 0.0% (0)

Amphotericin
B 98.7% (223) 1.3% (3)

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