Page 30 - Malaysian Journal of Health Promotion, Vol 4 (Supplementary 1) 2022

Malaysian Journal of Health Promotion, Vol 4 (Supplementary 1) 2022
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14 MOH-AMM Scientific Meeting 2022 in conjunction with 23 NIH Scientific Conference Abstract Book
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to analyze health outcomes. In this presentation, we focus on results of environmental
chemicals and body size. Recently some environmental chemicals showed the endocrine
disrupting properties and increase obesity, thus these chemicals are called obesogene. Our
findings indicate that higher levels of prenatal PFAS exposure were associated with decreased
birth size including ponderal index, increased levels of adiponectin, thyroid hormone and
antibody disruption, and increased or decreased levels of sex and steroid hormones at birth.
Higher levels of dioxins were associated with decreased birth size as well. Prenatal phthalate
esters showed inverse association with adiponectin and leptin at birth. Longer follow-up for
children is crucial in birth cohort studies to reinforce the Developmental Origins of Health and
Disease hypothesis.

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