Page 25 - ANTIFUNGAL SUSCEPTIBILITY OF CLINICAL YEAST ISOLATES 2018-2020

8. Trichosporon asahii (T. asahii)

A total of 35 Trichosporon asahii were analyzed from various type of clinical

specimens. The isolates were mainly from blood (12, 60.0%) followed by urine (8,
23.0%) (Table 8.1). The MIC ranges, MIC50 and MIC90 of seven antifungals are

shown in Table 8.2. There are no validated susceptibility criteria (clinical

breakpoints) provided by CLSI for antifungal agents tested. MICs provided are for

information only.

Table 8.1: Distribution of Trichosporon asahii isolated based on clinical
specimens in 2018-2020.
Specimen Type Number
Blood 21 60.0%
Urine 8 23.0%
CSF 1 3.0%
Tissue 1 3.0%
Others 4 11.0%
Total 35

Table 8.2: MIC50, MIC90 and MIC range values (µg/mL) for Trichosporon asahii in
2018-2020.
Antifungals MIC50 MIC90 MIC Range

Amphotericin B 2 32 0.125 - 32

Fluconazole 3 6 0.5 - 256

Itraconazole 0.5 1 0.125 - 4

Posaconazole * * *

Voriconazole 0.047 0.125 0.016 – 0.19

5-Fluorocytosine * * *

*The number of isolates tested were very low.

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