Page 22 - REAL ISSUES FOR COVID-19 VACCINE IMMUNIZATION & Pregnancy, Breastfeeding Mothers

Let's take a look at another systematic review “SARS-CoV-2 infection in pregnancy: A
systematic review and meta-analysis of clinical features and pregnancy outcomes” by Khalil
A. et al., also recently published about the implications of COVID-19 in pregnancy (Figure
8). This paper once again had similar outcomes to report. If you have COVID-19 in
pregnancy, the fetal distresses are higher, preterm deliveries are higher namely to aid
maternal respiration. Spontaneous preterm birth is also high, and as is the number of
caesarean sections is high.

Figure 8: Results from paper by Khalil A et al. (Khalil A, Kalafat E, Benlioglu C, O'Brien P,
Morris E, Draycott T, et al. SARS-CoV-2 infection in pregnancy: A systematic review and
meta-analysis of clinical features and pregnancy outcomes. EClinicalMedicine. 2020;25.
100446. doi: 10.1016/j.eclinm.2020.100446)

Since the BMJ report was published, a similar study (Figure 9) published in the JAMA
Internal Medicine in January this year, also showed similar evidence that the COVID-19 is
associated with significant medical implications, namely caesarean delivery, preterm birth,
ICU admissions and the need for ventilation.