Page 47 - INSTITUTE FOR MEDICAL RESEARCH ANNUAL REPORT 2020

IMR Annual Report 2020 31

HMRC Research

PRINCIPAL
NO. RESEARCH TITLE NMRR NUMBER INVESTIGATOR (PI)
OR CO-PRINCIPAL
INVESTIGATOR (CO-PI)
In vivo acute toxicity of four selected Malaysian
medicinal herbs, namely Euphorbia hirta (aerial),
1 NMRR-12-356-11163 Teh Bee Ping (PI)
Areca catechu (seeds), Acalypha indica (aerial),
and Cymbopogon nardus (aerial).
Metabolome classification of Euphorbia species Dr Maizatul Hasyima Research Centre (HMRC) Herbal Medicine
2 with antimicrobial potential via UHPLC-Orbitrap NMRR-18-2936-44243 Omar (PI), Dr Adlin
MS chemometrics Afzan (Co-PI)
Evaluation of anthocyanins-rich standardised
extract of H.sabdariffa L. Loaded niosomes Dr Maizatul Hasyima
3 NMRR- NH1015S020
for potential anti hypercholesterol and Omar (PI)
cardioprotective effect
Identification and isolation of advanced glycation
end-products inhibitors from Clinacanthus
4 NMRR-17-431-35176 Dr Adlin Afzan (PI)
nutans leaves extracts as potential anti-diabetic
agent
Isolation and characterisation of active
5 compounds from Dioscorea hispida dennst NMRR-17-432-35179 Nor Syaidatul Akmal
Mohd Yousof (PI)
tuber for antifungal activity
In vivo anti-dengue study of Schizophyllum
6 NMRR-17-2801-39102 Karithambigoi Ellon (PI)
commune aqueous extract in AG129 mice
Malaysian Herbal Monograph Development:
7 Schizophyllum commune, Dioscorea hispida and NMRR-12-1026-13937 Mohd Isa Wasiman (PI)
Smilax myosotiflora
Oral pharmacokinetic evaluation of freeze-dried Norzahirah Ahmad
8 NMRR-17-756-35404
Carica papaya leaves juice formulation in rats (Co-PI)

Serum postprandial metabolic responses to Norazlan
different fat-carbohydrate intake combination
9 NMRR-20-413-53007 Mohmad Misnan
using 1 H NMR metabolomics in diabetic, obese (Co-PI)
and atherogenic rodents

Immunomodulatory activities and its possible
10 mechanism of action of selected compounds NMRR-18-2937-44245 Nor Azrina Norahmad
(PI)
derived from Carica papaya
In vitro evaluation of antiviral activity of several
herbal formulations against the Severe Acute Dr Mohd Ridzuan Mohd
11 NMRR-20-874-54715
Syndrome Coronavirus 2 (SARS-CoV-2) in Abd Razak (PI)
COVID-19.