Page 37 - IMR Annual Report 2022: Institute for Medical Research
P. 37
Annual
IMR
Report2022 21
INSTITUTE FOR MEDICAL RESEARCH
Chimerism
Workshop
With Gendx at
Haematology Unit
Haemato-oncology Laboratory Tests in 2022
2022
Type of test Test performed
Samples Test
Leukemia Translocation Study Leukemia 30 Fusion Gene 817 31,336
BCR-ABL1 194 2,522
PML-RARA 46 506
AML Mutation Study FLT3-ITD 404 2,424
FLT3-D835 404 2,424
NPM1 291 3,942
CEBPA 122 2,806
c-KIT 51 306
BCR-ABL1 Kinase Domain Mutation Analysis
Leukemia 30 Fusion Gene Leukemia 30 Fusion Gene 67 3,507
Chimerism study
Leukemia 30 Fusion Gene Leukemia 30 Fusion Gene 523 8,322
Molecular Genetic Haematology Laboratory Tests
The Molecular Genetic Haematology Laboratory offers DNA analysis test for
thalassemia syndromes and haemoglobinopathies. These includes common
and variant mutations in both alpha and beta thalassemia.
Molecular Thalassemia
Molecular thalassaemia tests offered for the diagnosis of thalassaemia are
the amplification refractory mutation system (ARMS), GAP, and ARMS variant
for haemoglobin E (HbE) thalassaemia. The laboratory also offers additional Centre (CaRC) Cancer Research
panels for thalassaemia detection including:
• ARMS
• GAP
• and Multiplex Ligation-dependent Probe Amplification (MLPA)
• -, - and -sequencing
• A few modifiers i.e., XMN-1 polymorphism and triplication alpha
