Page 11 - ASYMPTOMATIC COVID-19 QUARANTINE DIGITAL SOLUTION: A PROOF-OF-CONCEPT STUDY (NMRR-20-2761-57684)

ASYMPTOMATIC COVID-19 QUARANTINE DIGITAL SOLUTION: A PROOF-OF-CONCEPT
STUDY
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Table 1. COVID-19 diagnosis based on clinical stages

Clinical Stage Clinical characteristics

1 Asymptomatic • Only RT-PCR test positive

• No clinical symptoms
• No chest imaging findings

2 Symptomatic • Upper respiratory tract infection (URTI) symptoms (e.g.,
without pharyngeal congestion, sore throat, cough or fever) for a
pneumonia
period less than 7 days

• No chest imaging findings

3 Pneumonia • URTI symptoms with others like vomiting, diarrhoea,
without hypoxia abdominal pain, myalgia, loss of smell/ taste

• Signs of increased work of breathing and increased

respiratory rate, but no hypoxemia
• Involvement of lungs as evident by chest imaging

4 Pneumonia with • Tachypnoea* with hypoxemia (SpO2<95% on room air)
hypoxia • CNS effect: Lethargy, decreased level of consciousness,
requiring
oxygen seizure
supplementation • GI effects: Dehydration, difficulty feeding, raised liver
therapy enzymes

• Myocardial effect: Raised Creatinine Kinase, Troponin
• Involvement of lungs as evident by chest imaging

5 Critically ill Rapid disease progression with:
• Respiratory failure requiring mechanical ventilation (acute
respiratory distress syndrome (ARDS))

• Persistent hypoxemia
• Septic shock
• Organ failure requiring invasive monitoring and mechanical

ventilation

TECHNICAL REPORT

DIGITAL HEALTH RESEARCH AND INNOVATION

INSTITUTE FOR CLINICAL RESEARCH
NATIONAL INSTITUTES OF HEALTH