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Mutations in Spike Protein of Malaysian SARS-

CoV-2 Strains

Table 1: Mutations in Spike Protein of Malaysian SARS-Co-V-2 Strains

We are looking at the mutations of SARs-CoV-2 spike protein. Active mutation means there
are amino acid changes. Silent mutation is without any amino acid change and it does not
cause any kind of structural change.

We observed in one case where a deletion occurred at 5-amino acid but we couldn’t see any
change in that particular strain of virus. Sometimes deletion can result in the “disappearance”
of that particular virus or the virus just “disappear”. Most importantly, the most frequently
reported mutation D614G in the spike protein was not found in any of the Malaysian strains.
Other reported mutations such as S943P, V367F, V483A were also not found in our strains.

That is all. Thank you for your attention.