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Severe COVID-19 Disease Group: Comorbid Group
The second subgroup of patients that get severe disease is the ones that get comorbid.
They have a viral response phase and then their comorbid medical condition worsens.
So classically, we see that in end-stage renal failure patients who are dialysis
dependent where they might require high-flow masks or even ventilation. But
predominantly, it is because the comorbid medical condition is getting worse. There
are some people who deteriorate purely because the co-morbid conditions are not in
control.
Diagram 7: Comorbid group as risk factor of severe COVID-19 disease