Page 18 - COVID-19-Mortality-review-in-Malaysia-and-updates-on-clinical-management-of-COVID-19
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What are the warning signs? What predicts that


                     these people are going to get severe disease?


               These   are   people   who   have   shortness   of   breath   on   exertion,   SpO2  that   is   low,
               persistent or new onset of fever. These are the clinical features that tell us that this

               person is going to deteriorate.


                   Laboratory markers that indicate deterioration/warning sign will be:

                   i) increasing C-reactive protein (CRP)/raised CRP. We don't have solid data for it
               but our impression is CRP value more than 70-100 seems to be a warning sign,
                   ii) increasing ferritin/ raised ferritin to more than 500

                   iii) persistently low or dropping lymphocyte count <1.0, again is a warning sign.
               They might get severe COVID-19.



                   Radiological criteria will be a multi-lobular involvement or rapidly worsening chest
               x-rays. These are the features we look for. In all the cases, we look for risk factors, the

               duration of disease, how long they've been sick and the warning signs.
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